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Pratiksha Dhote
Pratiksha Dhote

f Point of Care Diagnostics Testing in Acute Care Settings Focusing on the Rapid Analysis

Point of care diagnostics refer to medical testing performed at or near the site of patient care, bypassing the centralized laboratory. This decentralized approach utilizes portable, high-precision instruments to provide immediate results, which is essential in emergency departments, intensive care units, and ambulances where time-sensitive decisions are critical for survival.


By eliminating the need for specimen transport and manual processing, these devices significantly reduce the turnaround time for critical assays. Rapid access to arterial blood gas levels or cardiac troponin concentrations allows clinicians to differentiate between respiratory failure and myocardial infarction within minutes, ensuring that targeted treatment begins immediately.


The technology behind point of care testing (POCT) involves sophisticated biosensors and microfluidics. For example, handheld analyzers use electrochemical sensors to measure pH, pO2, and pCO2 in a single drop of whole blood. These sensors detect the electrical potential or current generated by chemical reactions on the electrode surface, converting biological information into digital data. In the context of infectious disease, lateral flow assays and miniaturized molecular platforms allow for the detection of viral antigens or nucleic acids at the bedside, which is vital for triage and infection control during outbreaks.


However, the implementation of POCT requires a rigorous quality management framework. Because these tests are often performed by nursing or paramedical staff rather than laboratory specialists, automated calibration and lockout features are necessary to prevent errors. Data must also be seamlessly integrated into the electronic health record to ensure a complete clinical history. While POCT provides speed, it is intended to complement, not replace, comprehensive laboratory analysis. The continued development of high-sensitivity assays on portable platforms is expanding the scope of POCT, allowing for the monitoring of coagulation profiles and even complex metabolic markers in diverse clinical environments.

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